Role of lipoprotein-associated phospholipase A2 in atherosclerosis
- PMID: 18489851
- DOI: 10.1007/s11883-008-0036-9
Role of lipoprotein-associated phospholipase A2 in atherosclerosis
Abstract
Lipoprotein-associated phospholipase A(2)(Lp-PLA(2)) is a biomarker that can be used to assess the risk for cardiovascular disease and events. In addition to being a useful marker of a risk factor, several studies suggest that Lp-PLA(2) has a pathophysiologic role in the atherosclerotic disease process. In this article, we review this aspect and its therapeutic implications.
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