Statement on guidance for genetic counseling in advanced paternal age
- PMID: 18496227
- PMCID: PMC3111019
- DOI: 10.1097/GIM.0b013e318176fabb
Statement on guidance for genetic counseling in advanced paternal age
Abstract
In 1996, a practice guideline on genetic counseling for advanced paternal age was published. The current document updates the state of knowledge of advanced paternal age effects on single gene mutations, chromosome anomalies, and complex traits.
References
RESOURCES
-
- Archer NP, Langlois PH, Suarez L, Brender J, et al. Association of paternal age with prevalence of selected birth defects. Birth Defects Res A Clin Mol Teratol. 2007;79:27–34. - PubMed
-
- Cedergren MI, Selbing AJ, Kallen BA. Risk factors for cardiovascular malformation—a study based on prospectively collected data. Scand J Work Environ Health. 2002;28:12–17. - PubMed
-
- MacDonald M, Hassold T, Harvey J, Wang LH, et al. The origin of 47, XXY and 47, XXX aneuploidy: heterogeneous mechanisms and the role of aberrant recombination. Hum Mol Genet. 1994;3:1365–1371. - PubMed
-
- Sherman SL, Freeman SB, Allen EG, Lamb NE. Risk factors for nondisjunction of Trisomy 21. Cytogenetic Genome Res. 2005;111:273–280. - PubMed
References
-
- Crow JF. Age and sex effects on human mutation rates: an old problem with new complexities. J Radiat Res. 2006;47(suppl):B72–B82. - PubMed
-
- Jung A, Schuppe HC, Schill WB. Are children of older fathers at risk for genetic disorders? Andrologia. 2003;35:191–199. - PubMed
-
- Splendore A, Jabs EW, Felix TM, Passos-Bueno MR. Parental origin of mutations in sporadic cases of Treacher Collins syndrome. Eur J Hum Genet. 2003;11:718–722. - PubMed
MeSH terms
LinkOut - more resources
Full Text Sources
Medical
