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Review
. 2008 Jul;38(4):775-86, vii.
doi: 10.1016/j.cvsm.2008.03.002.

Molecular virology of feline calicivirus

Patricia A Pesavento  1 , Kyeong-Ok Chang, John S L Parker
Affiliations
Review

Molecular virology of feline calicivirus

Patricia A Pesavento et al. Vet Clin North Am Small Anim Pract. 2008 Jul.

Abstract

Caliciviridae are small, nonenveloped, positive-stranded RNA viruses. Much of our understanding of the molecular biology of the caliciviruses has come from the study of the naturally occurring animal caliciviruses. In particular, many studies have focused on the molecular virology of feline calicivirus (FCV), which reflects its importance as a natural pathogen of cats. FCVs demonstrate a remarkable capacity for high genetic, antigenic, and clinical diversity; "outbreak" vaccine resistant strains occur frequently. This article updates the reader on the current status of clinical behavior and pathogenesis of FCV.

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