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Review
. 2008 Aug;24(6):645-71.
doi: 10.1007/s10554-008-9319-z. Epub 2008 May 27.

Coronary artery calcium screening: current status and recommendations from the European Society of Cardiac Radiology and North American Society for Cardiovascular Imaging

Matthijs Oudkerk  1 , Arthur E Stillman, Sandra S Halliburton, Willi A Kalender, Stefan Möhlenkamp, Cynthia H McCollough, Rozemarijn Vliegenthart, Leslee J Shaw, William Stanford, Allen J Taylor, Peter M A van Ooijen, Lewis Wexler, Paolo Raggi
Affiliations
Review

Coronary artery calcium screening: current status and recommendations from the European Society of Cardiac Radiology and North American Society for Cardiovascular Imaging

Matthijs Oudkerk et al. Int J Cardiovasc Imaging. 2008 Aug.

Abstract

Current guidelines and literature on screening for coronary artery calcium for cardiac risk assessment are reviewed for both general and special populations. It is shown that for both general and special populations a zero score excludes most clinically relevant coronary artery disease. The importance of standardization of coronary artery calcium measurements by multi-detector CT is discussed.

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Figures

Fig. 1
Fig. 1
Increase in relative risk (RR) with increasing CAC scores in asymptomatic persons in comparison to asymptomatic persons without CAC (modified from [20])
Fig. 2
Fig. 2
Annual rate of myocardial infarction or cardiac death in categories of CAC burden in persons at intermediate risk based on convention risk factor assessment. In persons with a high CAC score (> 400), the annual event rate exceeds the threshold for intensive risk factor modification, i.e. >2% per year (black line). A CAC score >400 in intermediate risk persons may therefore be considered as a risk equivalent (modified from [20])
Fig. 3
Fig. 3
The absolute and percent change in baseline Agatston score on serial CT imaging
Fig. 4
Fig. 4
Expected yearly rate of change (95% Confidence Intervals) from baseline for coronary artery calcium scores ranging from 0 to ≥1,000 Agatston Units (AU)
Fig. 5
Fig. 5
95% confidence intervals for repeatability of coronary artery calcium scores from 0 to ≥1,000
Fig. 6
Fig. 6
Summary meta-analysis of randomized control trials (RCT) on the rffect of Statin therapy (Rx) on CAC progression
See this image and copyright information in PMC

Comment in

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