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. 1991 Feb;120(1):75-81.
doi: 10.1007/BF01868593.

Transmembrane currents in frog olfactory cilia

S J Kleene  1 , R C Gesteland
Affiliations

Transmembrane currents in frog olfactory cilia

S J Kleene et al. J Membr Biol. 1991 Feb.

Abstract

We have measured transmembrane currents in intact single cilia from frog olfactory receptor neurons. A single cilium on a neuron was sucked into a patch pipette, and a high-resistance seal was formed near the base of the cilium. Action potentials could be induced by applying suction or a voltage ramp to the ciliary membrane. A transient current was seen in some cells on stimulation with odorants. After excision from the cell, most of the cilia showed increased conductance in a bath containing cAMP, indicating that the cytoplasmic face of the ciliary membrane was accessible to the bath. The estimated resistance of a single cilium was surprisingly low.

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