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. 1991 Jan;71(1):14-5, 4.

[Assay of moniliformin content in household grains from families in patients with Keshan disease]

[Article in Chinese]
Z Ji
  • PMID: 1850646

[Assay of moniliformin content in household grains from families in patients with Keshan disease]

[Article in Chinese]
Z Ji. Zhonghua Yi Xue Za Zhi. 1991 Jan.

Abstract

Ion-pairing extraction and high-performance liquid chromatography (HPLC) were employed for assaying moniliformin (a fungal toxin) content in the corn (Shaanxi) and rice (Yunnan) samples collected from families suffering from Ke-shan disease. The highest contents were found to be 264 micrograms/kg (corn) and 252 micrograms/kg (rice), while a rice sample from Beijing market showed none. The identity of moniliformin was confirmed by 2D-UV detection and co-HPLC with a synthetic toxin sample. These results strongly support the view that moniliformin is a pathogenic factor of Ke-shan disease.

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