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Review
. 2008 May 28;14(20):3117-22.
doi: 10.3748/wjg.14.3117.

Liver transplantation: yesterday, today and tomorrow

Osman Abbasoglu
Review

Liver transplantation: yesterday, today and tomorrow

Osman Abbasoglu. World J Gastroenterol. .

Abstract

With the advances in technical skills, management of postoperative complications and improvements in immunosuppressive drugs, liver transplantation is the standard treatment for many patients with chronic liver disease. Today, shortage of donor organs seems to be the major limiting factor for the application of liver transplantation. This review focuses on five issues that are challenging to clinical practice of liver transplantation and relevant to gastroenterologists. These include living donor liver transplantation, recurrent viral hepatitis, non-heart-beating donors, hepatocellular carcinoma, and ABO incompatible liver transplantation. Living donor and non-heart beating donor transplantations were initiated as a solution to increase the donor organ pool and it is expected that there will be an increase in the number of these donors. Recurrent hepatitis C and hepatocellular carcinoma following liver transplantation are among major problems and ongoing research in these diseases may lead to better outcomes in these recipients.

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References

    1. Groth CG, Brent LB, Calne RY, Dausset JB, Good RA, Murray JE, Shumway NE, Schwartz RS, Starzl TE, Terasaki PI, et al. Historic landmarks in clinical transplantation: conclusions from the consensus conference at the University of California, Los Angeles. World J Surg. 2000;24:834–843. - PMC - PubMed
    1. Starzl TE. History of clinical transplantation. World J Surg. 2000;24:759–782. - PMC - PubMed
    1. Raia S, Nery JR, Mies S. Liver transplantation from live donors. Lancet. 1989;2:497. - PubMed
    1. Japanese Liver Transplantation Society. Liver transplantation in Japan: registry by the Japanese Liver Transplantation Society. Jap J Transpl. 2003;38:401–408.
    1. Shneider BL, Emre S. Pediatric liver transplantation: past, present, and future. Liver Transpl. 2006;12:511–513. - PubMed

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