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. 2008 Jun;14(6):926-8.
doi: 10.3201/eid1406.071421.

Antibodies against Lagos bat virus in megachiroptera from West Africa

David T S Hayman  1 , Anthony R Fooks, Daniel Horton, Richard Suu-Ire, Andrew C Breed, Andrew A Cunningham, James L N Wood
Affiliations

Antibodies against Lagos bat virus in megachiroptera from West Africa

David T S Hayman et al. Emerg Infect Dis. 2008 Jun.

Abstract

To investigate the presence of Lagos bat virus (LBV)-specific antibodies in megachiroptera from West Africa, we conducted fluorescent antibody virus neutralization tests. Neutralizing antibodies were detected in Eidolon helvum (37%), Epomophorus gambianus (3%), and Epomops buettikoferi (33%, 2/6) from Ghana. These findings confirm the presence of LBV in West Africa.

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Figures

Figure 1
Figure 1
Antibody titers to Lagos bat virus (LBV) in 6 species of fruit bat in Ghana. An LBV-specific modified fluorescent antibody neutralization test was used to determine the level of antibody in bats; it used two 3-fold serial dilutions and derived a mean dilution at which the bats neutralized LBV. Bats with mean titers >9 were considered positive. The circle size represents the number of bats tested. 1, Epomops franqueti; 2, Epomophorus gambianus; 3, Epomops buettikoferi; 4, Eidolon helvum; 5, Hypsignathus monstrosus; 6, Nanonycteris veldkampii.
Figure 2
Figure 2
A) Density of a typical Eidolon helvum roost in the Accra colony. B) E. helvum as bushmeat in an Accra market.
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