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. 1991;103(2):177-82.
doi: 10.1007/BF02244200.

Effects of hypophysectomy and adrenalectomy on naloxone-induced analgesia

H Foo  1 , R F Westbrook
Affiliations

Effects of hypophysectomy and adrenalectomy on naloxone-induced analgesia

H Foo et al. Psychopharmacology (Berl). 1991.

Abstract

Experiment 1 demonstrated that pairings of the opiate antagonist, naloxone, with a heated floor came to induce analgesia, as indexed by the latencies with which rats licked their paws. This analgesia appears to be neurally mediated because it is unaffected by either hypophysectomy (experiment 2) or adrenalectomy (experiment 3). However, there was evidence for a pituitary involvement, as its removal potentiated the analgesic effect accruing from naloxone-stressor pairings.

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References

    1. Brain Res. 1978 Oct 20;155(1):69-90 - PubMed
    1. Science. 1977 Sep 30;197(4311):1367-9 - PubMed
    1. Physiol Behav. 1979 Jul;23(1):53-62 - PubMed
    1. Proc West Pharmacol Soc. 1981;24:323-6 - PubMed
    1. Pharmacol Biochem Behav. 1979 Mar;10(3):325-8 - PubMed

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