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. 2007 Jun;2(2):251-261.
doi: 10.1016/j.jsmc.2007.04.003.

Sleep Apnea and its association with the Stress System, Inflammation, Insulin Resistance and Visceral Obesity

Affiliations

Sleep Apnea and its association with the Stress System, Inflammation, Insulin Resistance and Visceral Obesity

G Trakada et al. Sleep Med Clin. 2007 Jun.
No abstract available

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Figures

Fig 1
Fig 1
Plasma TNFa and IL-6 levels in normal subjects and patients with EDS. (a) *P < 0.001 versus normal; (b) *P = 0.028 versus normal.
Fig 2
Fig 2
Visceral fat significantly correlated with indexes of sleep apnoea.formula image sleep apnoeics; formula image obese controls.
Fig 3
Fig 3
A model of the complex feed forward associations between visceral fat/insulin resistance, inflammatory cytokines, stress hormones, excessive daytime sleepiness and sleep apnoea.
Fig 4
Fig 4
Plasma IL-6 (top) and TNFa (bottom) are positively correlated with BMI in obese controls, but not in obese women with PCOS. (■) women with PCOS; (○), obese controls.
Fig 5
Fig 5
Sleep latencies during daytime testing with MSLT in the placebo (■) and etanercept (○) conditions. Each data point represents the mean±SE, P<0.05, adjusted change between placebo and etanercept.

References

    1. Vgontzas AN, Kales A. Sleep and its disorders. Annu Rev Med. 1999;50:387–400. - PubMed
    1. Young T, Palta M, Dempsey J, Skatrud J, Weber S, Badr S. The occurrence of sleep-disordered breathing among middle-age adults. N Engl J Med. 1993;328:1230–5. - PubMed
    1. Bixler EO, Vgontzas AN, Ten Have T, Tyson K, Kales A. Effects of age on sleep apnea in men: I. Prevalence and severity. Am J Respir Crit Care Med. 1998;157:144–8. - PubMed
    1. Bixler EO, Vgontzas AN, Lin H-M, Ten Have T, Rein J, Vela-Bueno A, Kales A. Prevalence of sleep-disordered breathing in women. Am J Respir Crit Care Med. 2001;163:608–13. - PubMed
    1. Young T, Peppard PE, Gottlieb DJ. Epidemiology of obstructive sleep apnea. A population health perspective. Am J Respir Crit Care Med. 2002;165:1217–39. - PubMed

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