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. 2007 Dec;3(6):1105-11.

Obstructive sleep apnea and cardiovascular risk

Punginathn Dorasamy  1
Affiliations

Obstructive sleep apnea and cardiovascular risk

Punginathn Dorasamy. Ther Clin Risk Manag. 2007 Dec.

Abstract

Obstructive sleep apnea (OSA) is a form of sleep disordered breathing characterized by episodes of apnea (during sleep) lasting at least 10 seconds per episode. The apneic periods are associated with arterial hypoxemia and disruption of normal sleep as a result of awakenings. It is increasingly being recognized that OSA is a public health hazard and there is increasing evidence that it is associated with an increase in morbidity (and possibly mortality). Patients with OSA also utilize the healthcare resources at higher rates than control patients long before their diagnosis is confirmed. Early recognition of this condition may lead to earlier treatments (eg, nasal CPAP) with reduction of the risk of cardiovascular diseases such as hypertension, ischemic heart disease, arrhythmias, platelet activation and pulmonary hypertension.

Keywords: C-Reactive protein (CRP); Cheynes Stokes respiration-central sleep apnea (CSR-CSA); apnea-hypopnea index (AHI); obstructive sleep apnea (OSA); polysomnography, overlap syndrome; sleep disordered breathing (SDB).

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