Epithelial-mesenchymal transition and the stem cell phenotype
- PMID: 18522839
- DOI: 10.1016/j.stem.2008.05.007
Epithelial-mesenchymal transition and the stem cell phenotype
Abstract
Epithelial-mesenchymal transition (EMT) is a developmental process in which epithelial cells acquire the motile, migratory properties of mesenchymal cells. In a recent issue of Cell, Mani et al. (2008) show that induction of EMT stimulates cultured breast cells to adopt characteristics of stem cells.
Comment on
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The epithelial-mesenchymal transition generates cells with properties of stem cells.Cell. 2008 May 16;133(4):704-15. doi: 10.1016/j.cell.2008.03.027. Cell. 2008. PMID: 18485877 Free PMC article.
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