Home is where the heart is: via the FROUNT
- PMID: 18522840
- DOI: 10.1016/j.stem.2008.05.012
Home is where the heart is: via the FROUNT
Abstract
In this issue of Cell Stem Cell, Belema-Bedada et al. (2008) describe a novel mechanism by which bone marrow-derived adult mesenchymal stem cells migrate to sites of damaged heart tissue. This process is dependent on the intracellular adaptor molecule FROUNT, which interacts with the chemokine receptor CCR2.
Comment on
-
Efficient homing of multipotent adult mesenchymal stem cells depends on FROUNT-mediated clustering of CCR2.Cell Stem Cell. 2008 Jun 5;2(6):566-75. doi: 10.1016/j.stem.2008.03.003. Cell Stem Cell. 2008. PMID: 18522849
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources