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. 2008 Sep;31(9):1783-8.
doi: 10.2337/dc08-0212. Epub 2008 Jun 3.

Diabetes and other disorders of glycemia in a rural South African community: prevalence and associated risk factors

Ayesha A Motala  1 , Tonya Esterhuizen, Eleanor Gouws, Fraser J Pirie, Mahomed A K Omar
Affiliations

Diabetes and other disorders of glycemia in a rural South African community: prevalence and associated risk factors

Ayesha A Motala et al. Diabetes Care. 2008 Sep.

Abstract

Objective: The purpose of this study was to determine the prevalence of diabetes, impaired glucose tolerance (IGT), impaired fasting glycemia (IFG), and associated risk factors in a rural South African black community.

Research design and methods: This was a cross-sectional survey conducted by random cluster sampling of adults aged >15 years. Participants had a 75-g oral glucose tolerance test using the 1998 World Health Organization criteria for disorders of glycemia.

Results: Of 1,300 subjects selected, 1,025 subjects (815 women) participated (response rate 78.9%). The overall age-adjusted prevalence of diabetes was 3.9%, IGT 4.8%, and IFG 1.5%. The prevalence was similar in men and women for diabetes (men 3.5%; women 3.9%) and IGT (men 4.6%; women 4.7%) but higher in men for IFG (men 4.0%; women 0.8%). The prevalence of diabetes and IGT increased with age both in men and women, with peak prevalence in the 55- to 64-year age-group for diabetes and in the >or=65-year age-group for IGT. Of the cases of diabetes, 84.8% were discovered during the survey. In multivariate analysis, the significant independent risk factors associated with diabetes included family history (odds ratio 3.5), alcohol ingestion (2.8), waist circumference (1.1), systolic blood pressure (1.0), serum triglycerides (2.3), and total cholesterol (1.8); hip circumference was protective (0.9).

Conclusions: There is a moderate prevalence of diabetes and a high prevalence of total disorders of glycemia, which suggests that this community, unlike other rural communities in Africa, is well into an epidemic of glucose intolerance. There is a low proportion of known diabetes and a significant association with potentially modifiable risk factors.

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References

    1. McLarty DG, Pollitt C, and Swai ABM: Diabetes in Africa. Diabet Med 7:670-684,1990 - PubMed
    1. Motala AA, Omar MA, Pirie FJ: Diabetes in Africa: epidemiology of type 1 and type 2 diabetes in Africa. J Cardiovasc Risk 10:77–83, 2003 - PubMed
    1. International Diabetes Federation: Diabetes Atlas. 3rd ed. Brussels, International Diabetes Federation, 2006
    1. World Health Organization: Diabetes Mellitus: Report of a WHO Study Group. Geneva, World Health Org., 1985 (Tech. Rep. Ser., no. 727) - PubMed
    1. Levitt NS, Unwin NC, Bradshaw D, Kitange HM, Mbanya J-CN, Mollentze WF, Omar MAK, Motala AA, Joubert G, Masuki G, Machibya H: Application of the new ADA criteria for the diagnosis of diabetes to population studies in sub-Saharan Africa. Diabet Med 17: 381–385, 2000 - PubMed

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