Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 2008 Aug;46(8):2780-2.
doi: 10.1128/JCM.00557-08. Epub 2008 Jun 4.

Evaluation of StrepB carrot broth versus Lim broth for detection of group B Streptococcus colonization status of near-term pregnant women

D L Church  1 , Heather Baxter, Tracie Lloyd, Beverley Miller, Sameer Elsayed
Affiliations
Comparative Study

Evaluation of StrepB carrot broth versus Lim broth for detection of group B Streptococcus colonization status of near-term pregnant women

D L Church et al. J Clin Microbiol. 2008 Aug.

Abstract

The performance of StrepB Carrot Broth (SCB) versus group B Lim broth (LIM) for detection of group B streptococcus (GBS) colonization status in near-term pregnant women (35 to 37 weeks of gestation) was evaluated. Dually collected vaginal/rectal swabs from 279 women enrolled from a single large maternity clinic were analyzed. Fifty (18%) women were colonized by GBS according to both methods. SCB had excellent diagnostic performance compared to LIM, with sensitivity, specificity, positive predictive value, and negative predictive value of 92%, 100%, 100%, and 98.3%, respectively. Improved diagnostic efficiency due to direct reporting of GBS cases based on an orange color change in the SCB decreased overall labor and material costs.

PubMed Disclaimer

Figures

FIG. 1.
FIG. 1.
Implementation of SCB for GBS detection. PYR, pyroglutamyl aminopeptidase.
See this image and copyright information in PMC

References

    1. American Academy of Pediatrics Committee on Infectious Diseases and Committee on Fetus and Newborn. 1997. Revised guidelines for prevention of early-onset group B streptococcal (GBS) infection. Pediatrics 99489-496. - PubMed
    1. American College of Obstetrics and Gynecologists. 1996. ACOG committee opinion. Prevention of early-onset group B streptococcal disease in newborns, no. 173, June 1996. Int. J. Gynaecol. Obstet. 54197-205. - PubMed
    1. Centers for Disease Control and Prevention. 2002. Prevention of perinatal group B streptococcal disease: revised guidelines from CDC. Centers for Disease Control and Prevention, Atlanta, GA.
    1. Davies, H. D., C. E. Adair, E. S. Partlow, R. Sauve, D. E. Low, and A. McGeer. 1999. Two-year survey of Alberta laboratories processing of antenatal group B streptococcal (GBS) screening specimens: implications for GBS screening programs. Diagn. Microbiol. Infect. Dis. 35169-176. - PubMed
    1. Edwards, M. S., and C. J. Baker. 2001. Group B streptococcal infections, p. 1091-1156. In J. S. Remington and J. O. Klein (ed.), Infectious diseases of the fetus and newborn infant. W.B. Saunders, Philadelphia, PA.

Publication types