Analysis of the RNA species isolated from defective particles of vesicular stomatitis virus
- PMID: 185328
- DOI: 10.1099/0022-1317-33-1-51
Analysis of the RNA species isolated from defective particles of vesicular stomatitis virus
Abstract
Serial high multiplicity passage of a cloned stock of vesicular stomatitis virus was found to generate defective interfering particles containing three size classes of RNA, with sedimentaiton coefficients of 31 S, 23 S and 19 S. The 31 S and 23 S RNA species were found to be complementary to both the 12 to 18 S and 31 S size classes of VSV mRNAs. The 19 S class of RNA was found to be partially base-paired. All three RNA species were found to contain ppAp at their 5' termini.
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