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Randomized Controlled Trial
. 2008 Sep;102(3):259-62.
doi: 10.1016/j.ijgo.2008.04.009. Epub 2008 Jun 4.

Effect of intramuscular administration of dexamethasone on the duration of labor

Maryam Kashanian  1 , Farideh Dadkhah, Fattaneh Mokhtari
Affiliations
Randomized Controlled Trial

Effect of intramuscular administration of dexamethasone on the duration of labor

Maryam Kashanian et al. Int J Gynaecol Obstet. 2008 Sep.

Abstract

Objective: To evaluate the effect of dexamethasone administration on labor duration.

Method: In this controlled trial 122 nulliparous women with a full-term pregnancy and a Bishop score of 7 or greater were randomly assigned to receive a single 8-mg dose of dexamethasone or placebo 6 hours before initiation of labor induction.

Results: The interval between initiation of labor induction and beginning of the active phase of labor was shorter in the dexamethasone than in the control group (3.09+/-1.5 hours vs. 4.21+/-1.8 hours; P=0.001). The duration of the second stage of labor was also shorter in the dexamethasone group (22.23+/-16.09 minutes vs. 29.01+/-15.32 minutes; P=0.014).

Conclusion: The administration of dexamethasone was found to shorten labor duration.

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