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. 2008 Jun;33(2):259-67.
doi: 10.1007/s12038-008-0043-6.

Production of paclitaxel by Fusarium solani isolated from Taxus celebica

B V S K Chakravarthi  1 , Prasanta Das, Kalpana Surendranath, Anjali A Karande, Chelliah Jayabaskaran
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Production of paclitaxel by Fusarium solani isolated from Taxus celebica

B V S K Chakravarthi et al. J Biosci. 2008 Jun.

Abstract

A fungus was isolated from the stem cuttings of Taxus celebica, which produced paclitaxel in liquid-grown cultures. The fungus was identified as Fusarium solani based on colony characteristics, morphology of conidia and the 26S rDNA sequence. Paclitaxel was identified by chromatographic and spectroscopic comparison with authentic paclitaxel and its cytotoxic activity towards Jurkat cells in vitro.

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