Comment
doi: 10.1016/j.devcel.2008.05.011.
Hematopoietic lineage commitment: miRNAs add specificity to a widely expressed transcription factor
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- PMID: 18539110
- DOI: 10.1016/j.devcel.2008.05.011
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Comment
Hematopoietic lineage commitment: miRNAs add specificity to a widely expressed transcription factor
Dev Cell.
2008 Jun.
Free article
Abstract
MicroRNAs are important regulators of normal and malignant hematopoiesis. A paper by Lu et al. in this issue of Developmental Cell demonstrates how one microRNA, miR-150, plays a critical role in commitment of the erythroid-megakaryocyte progenitor by modulating the level of the widely expressed transcription factor MYB (or c-Myb).
Comment on
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MicroRNA-mediated control of cell fate in megakaryocyte-erythrocyte progenitors.Dev Cell. 2008 Jun;14(6):843-53. doi: 10.1016/j.devcel.2008.03.012. Dev Cell. 2008. PMID: 18539114 Free PMC article.
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