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Review
. 2008 Aug;74(16):4985-96.
doi: 10.1128/AEM.00753-08. Epub 2008 Jun 6.

Ecological role of lactobacilli in the gastrointestinal tract: implications for fundamental and biomedical research

Jens Walter  1
Affiliations
Review

Ecological role of lactobacilli in the gastrointestinal tract: implications for fundamental and biomedical research

Jens Walter. Appl Environ Microbiol. 2008 Aug.
No abstract available

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Figures

FIG. 1.
FIG. 1.
(A to D) Competition experiments performed between the wild-type L. reuteri strains 100-23C (A and B), 100-23 (C), and TMW 1.106 (D) and the isogenic mutants with insertional inactivations of the lsp (A), msrB (B), dltA (C), and inu (D) genes (102, 105, 106). Mixtures of mutants and wild type (1:1) were used to inoculate Lactobacillus-free mice, and the percentages of mutants in the total Lactobacillus population were determined at 7 days in the forestomach (FS), jejunum (JJ), and cecum (Cec). Data points of individual animals are connected by lines. (E) DGGE analysis of PCR-amplified 16S rRNA gene fragments obtained with the primers Lac1 and Lac2GC and DNA isolated from the crop, ileum (Ile), and cecum (Cec) of four chickens (age, 42 days) that were floor reared at the University of Nebraska (I. Martínez, S. Scheideler, and J. Walter, unpublished data). M, marker representing species isolated from the chickens. DGGE was performed as described by Walter et al. (104). (F) DGGE analysis of PCR-amplified 16S rRNA gene fragments obtained with the primers Lac1 and Lac2GC and DNA isolated from the esophagus close to the stomach (Eso), the pars esophagus (Pars), the stomach contents (Stom), the duodenum (Duo), jejunum (JJ), ileum (Ile), cecum (Cec), proximal colon (PrCol), and distal colon (DisCol) of a male, castrated pig (age, 10 weeks) that was reared at the University of Nebraska (I. Martínez, T. Burkey, and J. Walter, unpublished data). M, marker representing species commonly present in pigs. DGGE was performed as described by Walter et al. (104).
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