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. 1991 May;35(5):1014-6.
doi: 10.1128/AAC.35.5.1014.

Lack of ciprofloxacin ototoxicity after repeated ototopical application

J Claes  1 , P J Govaerts, P H Van de Heyning, S Peeters
Affiliations

Lack of ciprofloxacin ototoxicity after repeated ototopical application

J Claes et al. Antimicrob Agents Chemother. 1991 May.

Abstract

The possible side effects of ototopically applied ciprofloxacin on inner ear function were investigated. The hearing function of pigmented guinea pigs was evaluated by daily frequency-specific evoked response audiometry after repeated application of the drug to both ears. Ciprofloxacin appeared to have no statistically significant effect on the hearing thresholds of the experimental animals.

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References

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