Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1991 May;35(5):983-5.
doi: 10.1128/AAC.35.5.983.

Modulation of the intestinal flora of mice by treatment with aztreonam and tigemonam

M L van Ogtrop  1 , H F Guiot, H Mattie, E van Strijen, B R Sekh, R van Furth
Affiliations

Modulation of the intestinal flora of mice by treatment with aztreonam and tigemonam

M L van Ogtrop et al. Antimicrob Agents Chemother. 1991 May.

Abstract

Oral and parenteral administration of aztreonam and oral administration of tigemonam to conventional mice caused a decrease in the number of aerobic gram-negative rods in the feces. Oral treatment with high doses of aztreonam (greater than or equal to 25 mg/kg/day) and tigemonam (100 mg/kg/day) adversely influenced colonization resistance, whereas oral treatment with lower doses of the monobactams or parenteral treatment with aztreonam did not.

PubMed Disclaimer

References

    1. Antimicrob Agents Chemother. 1991 May;35(5):976-82 - PubMed
    1. Antimicrob Agents Chemother. 1991 Mar;35(3):417-22 - PubMed
    1. Antimicrob Agents Chemother. 1984 Dec;26(6):941-3 - PubMed
    1. J Infect Dis. 1984 Nov;150(5):636-42 - PubMed
    1. Antimicrob Agents Chemother. 1987 Feb;31(2):226-9 - PubMed

Publication types

LinkOut - more resources