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Comment
. 2008 Jun 15;111(12):5420-1.
doi: 10.1182/blood-2008-01-135392.

SNPing away at sickle cell pathophysiology

Martin H Steinberg  1
Affiliations
Comment

SNPing away at sickle cell pathophysiology

Martin H Steinberg. Blood. .

Abstract

In this issue of Blood, Ashley-Koch and coworkers report that, in sickle cell disease–related pulmonary hypertension, SNPs in several genes of the TGF-β/BMP superfamily are associated with this complication.

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Conflict of interest statement

Conflict-of-interest disclosure: The author declares no competing financial interests. ■

Figures

None
Some of the subphenotypes of sickle cell anemia and the genes in which SNPs have been associated with these phenotypes.
See this image and copyright information in PMC

Comment on

References

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    1. Saxena R, Voight BF, Lyssenko V, et al. Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science. 2007;316:1331–1336. - PubMed