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. 2008 Jun 10;5(6):e130.
doi: 10.1371/journal.pmed.0050130.

How might cocaine interfere with brain development?

Affiliations

How might cocaine interfere with brain development?

Steven E Hyman. PLoS Med. .

Abstract

Steven Hyman discusses a new study using cell culture and fetal rat models to investigate mechanisms by which cocaine might decrease the number of neurons in the brain.

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Conflict of interest statement

Competing Interests: The author has declared that no competing interests exist.

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References

    1. Chiriboga CA, Kuhn L, Wasserman GA. Prenatal cocaine exposures and dose-related cocaine effects on infant tone and behavior. Neurotoxicol Teratol. 2007;29:323–330. - PMC - PubMed
    1. Singer LT, Arendt R, Minnes S, Farkas K, Salvator A, et al. Cognitive and motor outcomes of cocaine-exposed infants. JAMA. 2002;287:1952–1960. - PMC - PubMed
    1. Noland JS, Singer LT, Short EJ, Minnes S, Arendt RE, et al. Prenatal drug exposure and selective attention in preschoolers. Neurotoxicol Teratol. 2005;27:429–438. - PubMed
    1. Lee C-T, Chen J, Hayashi T, Tsai S-Y, Sanchez JF, et al. A mechanism responsible for the inhibition of neural progenitor cell proliferation by cocaine. PLoS Med. 2008;5:e117. doi: 10.1371/journal.pmed.0050117. - DOI - PMC - PubMed
    1. Malanga CJ, Pejchal M, Kosofsky BE. Prenatal exposure to cocaine alters the development of conditioned place-preference to cocaine in adult mice. Pharmacol Biochem Behav. 2007;87:462–471. - PMC - PubMed