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Comparative Study
. 1991 Feb;111(2):170-2.

[The evaluation of the efficacy of antihypoxic agents lowering hemoglobin oxygen affinity in acute cerebral ischemia]

[Article in Russian]
T M Plotnikova, M B Plotnikov, T G Bazhenova
  • PMID: 1854961
Comparative Study

[The evaluation of the efficacy of antihypoxic agents lowering hemoglobin oxygen affinity in acute cerebral ischemia]

[Article in Russian]
T M Plotnikova et al. Biull Eksp Biol Med. 1991 Feb.

Abstract

Influence of natrii hydroxybutyrate (100 mg/kg), ascorbate (100 mg/kg), cavinton (5 mg/kg), bemitil (50 mg/kg), ethomersol (50 mg/kg) on Hb-O2 affinity and cortex PO2 after both carotid artery occlusion in rats was investigated. Correlation (r-0.87; P less than 0.05) between lowering of Hb-O2 affinity and antihypoxic effect was demonstrated in the line of these drugs.

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