Statistical Methods for Mapping Multiple QTL

doi:10.1155/2008/286561

. 2008:2008:286561.

doi: 10.1155/2008/286561.

Statistical Methods for Mapping Multiple QTL

Wei Zou¹, Zhao-Bang Zeng

Affiliations

PMID: 18551187
PMCID: PMC2423007
DOI: 10.1155/2008/286561

Statistical Methods for Mapping Multiple QTL

Wei Zou et al. Int J Plant Genomics. 2008.

. 2008:2008:286561.

doi: 10.1155/2008/286561.

Authors

Wei Zou¹, Zhao-Bang Zeng

Affiliation

¹ Bioinformatics Research Center, North Carolina State University, Raleigh, 27695, USA.

PMID: 18551187
PMCID: PMC2423007
DOI: 10.1155/2008/286561

Abstract

Since Lander and Botstein proposed the interval mapping method for QTL mapping data analysis in 1989, tremendous progress has been made in the last many years to advance new and powerful statistical methods for QTL analysis. Recent research progress has been focused on statistical methods and issues for mapping multiple QTL together. In this article, we review this progress. We focus the discussion on the statistical methods for mapping multiple QTL by maximum likelihood and Bayesian methods and also on determining appropriate thresholds for the analysis.

PubMed Disclaimer

Cited by

Recombination locations and rates in beef cattle assessed from parent-offspring pairs.
Weng ZQ, Saatchi M, Schnabel RD, Taylor JF, Garrick DJ. Weng ZQ, et al. Genet Sel Evol. 2014 May 29;46(1):34. doi: 10.1186/1297-9686-46-34. Genet Sel Evol. 2014. PMID: 24885305 Free PMC article.
Identification of quantitative trait loci of agronomic traits in bread wheat using a Pamyati Azieva × Paragon mapping population harvested in three regions of Kazakhstan.
Amalova A, Yermekbayev K, Griffiths S, Abugalieva S, Babkenov A, Fedorenko E, Abugalieva A, Turuspekov Y. Amalova A, et al. PeerJ. 2022 Nov 9;10:e14324. doi: 10.7717/peerj.14324. eCollection 2022. PeerJ. 2022. PMID: 36389412 Free PMC article.
Enrichment of statistical power for genome-wide association studies.
Li M, Liu X, Bradbury P, Yu J, Zhang YM, Todhunter RJ, Buckler ES, Zhang Z. Li M, et al. BMC Biol. 2014 Oct 17;12:73. doi: 10.1186/s12915-014-0073-5. BMC Biol. 2014. PMID: 25322753 Free PMC article.
DNA fingerprinting in botany: past, present, future.
Nybom H, Weising K, Rotter B. Nybom H, et al. Investig Genet. 2014 Jan 3;5(1):1. doi: 10.1186/2041-2223-5-1. Investig Genet. 2014. PMID: 24386986 Free PMC article.
Genomic breeding value prediction and QTL mapping of QTLMAS2010 data using Bayesian Methods.
Sun X, Habier D, Fernando RL, Garrick DJ, Dekkers JC. Sun X, et al. BMC Proc. 2011 May 27;5 Suppl 3(Suppl 3):S13. doi: 10.1186/1753-6561-5-S3-S13. BMC Proc. 2011. PMID: 21624169 Free PMC article.

See all "Cited by" articles

References

1. Zeng Z-B, Kao C-H, Basten CJ. Estimating the genetic architecture of quantitative traits. Genetical Research. 1999;74(3):279–289. - PubMed
1. Sax K. The association of size differences with seed-coat pattern and pigmentation in phaseolus vulgaris. Genetics. 1923;8(6):552–560. - PMC - PubMed
1. Mackay TFC. The genetic architecture of quantitative traits. Annual Review of Genetics. 2001;35:303–339. - PubMed
1. Lander ES, Botstein S. Mapping mendelian factors underlying quantitative traits using RFLP linkage maps. Genetics. 1989;121(1):185–199. - PMC - PubMed
1. Haley CS, Knott SA. A simple regression method for mapping quantitative trait loci in line crosses using flanking markers. Heredity. 1992;69(4):315–324. - PubMed

LinkOut - more resources

Full Text Sources

[1] Zeng Z-B, Kao C-H, Basten CJ. Estimating the genetic architecture of quantitative traits. Genetical Research. 1999;74(3):279–289. - PubMed

[2] Zeng Z-B, Kao C-H, Basten CJ. Estimating the genetic architecture of quantitative traits. Genetical Research. 1999;74(3):279–289. - PubMed

[3] Sax K. The association of size differences with seed-coat pattern and pigmentation in phaseolus vulgaris. Genetics. 1923;8(6):552–560. - PMC - PubMed

[4] Sax K. The association of size differences with seed-coat pattern and pigmentation in phaseolus vulgaris. Genetics. 1923;8(6):552–560. - PMC - PubMed

[5] Mackay TFC. The genetic architecture of quantitative traits. Annual Review of Genetics. 2001;35:303–339. - PubMed

[6] Mackay TFC. The genetic architecture of quantitative traits. Annual Review of Genetics. 2001;35:303–339. - PubMed

[7] Lander ES, Botstein S. Mapping mendelian factors underlying quantitative traits using RFLP linkage maps. Genetics. 1989;121(1):185–199. - PMC - PubMed

[8] Lander ES, Botstein S. Mapping mendelian factors underlying quantitative traits using RFLP linkage maps. Genetics. 1989;121(1):185–199. - PMC - PubMed

[9] Haley CS, Knott SA. A simple regression method for mapping quantitative trait loci in line crosses using flanking markers. Heredity. 1992;69(4):315–324. - PubMed

[10] Haley CS, Knott SA. A simple regression method for mapping quantitative trait loci in line crosses using flanking markers. Heredity. 1992;69(4):315–324. - PubMed

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

Statistical Methods for Mapping Multiple QTL

Affiliation

Statistical Methods for Mapping Multiple QTL

Authors

Affiliation

Abstract

Similar articles

Cited by

References

LinkOut - more resources

Full Text Sources