doi: 10.1021/cc8000103.
Epub 2008 Jun 14.
Simple synthesis of 7H-phenaleno[1,2-b]furan-7-one derivatives by one-pot, three-component reactions
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- PMID: 18553985
- DOI: 10.1021/cc8000103
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Simple synthesis of 7H-phenaleno[1,2-b]furan-7-one derivatives by one-pot, three-component reactions
J Comb Chem.
2008 Jul-Aug.
Abstract
The reaction of alkyl isocyanides with various aldehydes and 3-hydroxy-1 H-phenalene-1-one is described. The protocol offers facile and efficient synthesis of biologically interesting 9-(alkyl or arylamino)-7 H-phenaleno[1,2- b]furan-7-one derivatives from readily available starting materials in high yields.
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