Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2008 Jun 15;586(12):2825-6.
doi: 10.1113/jphysiol.2008.156398.

Male and female equality: still far from goal

Liliana Sintra Grilo  1 , Hugues Abriel
Affiliations
Comment

Male and female equality: still far from goal

Liliana Sintra Grilo et al. J Physiol. .
No abstract available

PubMed Disclaimer

Figures

Figure 1
Figure 1. Scheme illustrating the ventricular action potential and surface electrocardiogram (ECG)
The QT interval – time between start of the QRS complex and end of T wave – reflects, in part, the action potential duration (APD). Females have a longer APD and QT interval than males. The repolarization reserve of females is smaller; hence, they are at higher risk for Torsades de Pointes when exposed to factors such as drugs blocking the hERG channel delaying further the repolarization.
See this image and copyright information in PMC

Comment on

References

    1. Abi-Gerges N, Philp K, Pollard C, Wakefield I, Hammond TG, Valentin JP. Fundam Clin Pharmacol. 2004;18:139–151. - PubMed
    1. Abriel H, Schlapfer J, Keller DI, Gavillet B, Buclin T, Biollaz J, Stoller R, Kappenberger L. Swiss Med Wkly. 2004;134:685–694. - PubMed
    1. Burke JH, Ehlert FA, Kruse JT, Parker MA, Goldberger JJ, Kadish AH. Am J Cardiol. 1997;79:178–181. - PubMed
    1. Drici MD, Burklow TR, Haridasse V, Glazer RI, Woosley RL. Circulation. 1996;94:1471–1474. - PubMed
    1. Kadish AH, Greenland P, Limacher MC, Frishman WH, Daugherty SA, Schwartz JB. Ann Noninvasive Electrocardiol. 2004;9:366–374. - PMC - PubMed

Publication types

LinkOut - more resources