"MGMT for pt mgmt": is methylguanine-DNA methyltransferase testing ready for patient management?
- PMID: 18556768
- PMCID: PMC2438198
- DOI: 10.2353/jmoldx.2008.080043
"MGMT for pt mgmt": is methylguanine-DNA methyltransferase testing ready for patient management?
Abstract
This Commentary reports on a robust quantitative assay for the interpretation of O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation assays that should facilitate the comparison and implementation of such assays across laboratories.
Comment on
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Validation of real-time methylation-specific PCR to determine O6-methylguanine-DNA methyltransferase gene promoter methylation in glioma.J Mol Diagn. 2008 Jul;10(4):332-7. doi: 10.2353/jmoldx.2008.070169. Epub 2008 Jun 13. J Mol Diagn. 2008. PMID: 18556773 Free PMC article.
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