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Case Reports
. 2008 Apr;21(4):381-4.
doi: 10.1515/jpem.2008.21.4.381.

Anaphylactic reaction to recombinant insulin-like growth factor-I

Erika Torjusen  1 , Jose Calderon, Scott A Rivkees
Affiliations
Case Reports

Anaphylactic reaction to recombinant insulin-like growth factor-I

Erika Torjusen et al. J Pediatr Endocrinol Metab. 2008 Apr.

Abstract

Mecasermin [rDNA] (Increlex; Tercica, Inc.) is recombinant insulin-like growth factor-I (IGF-I) that has been approved to treat growth failure in children with severe primary IGF-I deficiency. Serious allergic reactions related to Increlex therapy have not been reported. We report a 13 year-old male who developed life-threatening anaphylaxis early in the course of Increlex therapy.

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