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Review
. 2008 Jun 16:6:58.
doi: 10.1186/1477-7819-6-58.

Male breast cancer: is the scenario changing

Kaiyumars B Contractor  1 , Kanchan Kaur, Gabriel S Rodrigues, Dhananjay M Kulkarni, Hemant Singhal
Affiliations
Review

Male breast cancer: is the scenario changing

Kaiyumars B Contractor et al. World J Surg Oncol. .

Abstract

Background: The overall incidence of male breast cancer is around 1% of all breast cancers and is on the rise. In this review we aim to present various aspects of male breast cancer with particular emphasis on incidence, risk factors, patho-physiology, treatment, prognostic factors, and outcome.

Methods: Information on all aspects of male breast cancer was gathered from available relevant literature on male breast cancer from the MEDLINE database over the past 32 years from 1975 to 2007. Various reported studies were scrutinized for emerging evidence. Incidence data were also obtained from the IARC, Cancer Mondial database.

Conclusion: There is a scenario of rising incidence, particularly in urban US, Canada and UK. Even though more data on risk factors is emerging about this disease, more multi-institutional efforts to pool data with large randomized trials to show treatment and survival benefits are needed to support the existing vast emerging knowledge about the disease.

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Figures

Figure 1
Figure 1
Age wise adjusted incidence of male and female breast cancer (SEER's 12 Registry database, 1992–2000).
Figure 2
Figure 2
Stage related survival in male breast cancer.
See this image and copyright information in PMC

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