doi: 10.1021/np800187f.
Epub 2008 Jun 18.
C-geranylated chalcones from the stems of Angelica keiskei with superoxide-scavenging activity
Affiliations
- PMID: 18558745
- DOI: 10.1021/np800187f
Item in Clipboard
C-geranylated chalcones from the stems of Angelica keiskei with superoxide-scavenging activity
J Nat Prod.
2008 Jul.
Abstract
An ethyl acetate-soluble fraction of a methanol extract from the stems of Angelica keiskei was subjected to chromatographic separation to give three new chalcones, designated as xanthokeismins A-C (1-3), in addition to a known chalcone, xanthoangelol B (4). The structures of 1-3 were determined on the basis of the analysis of their spectroscopic data. Compounds 1-4 exhibited potent superoxide-scavenging activity.
Similar articles
-
Chalcones and other compounds from the exudates of Angelica keiskei and their cancer chemopreventive effects.J Nat Prod. 2006 Jan;69(1):38-42. doi: 10.1021/np058080d. J Nat Prod. 2006. PMID: 16441065
-
PTP1B inhibitors from stems of Angelica keiskei (Ashitaba).Bioorg Med Chem Lett. 2015;25(10):2028-32. doi: 10.1016/j.bmcl.2015.04.003. Epub 2015 Apr 4. Bioorg Med Chem Lett. 2015. PMID: 25891102
-
Beneficial effect of xanthoangelol, a chalcone compound from Angelica keiskei, on lipid metabolism in stroke-prone spontaneously hypertensive rats.Clin Exp Pharmacol Physiol. 2007 Mar;34(3):238-43. doi: 10.1111/j.1440-1681.2007.04578.x. Clin Exp Pharmacol Physiol. 2007. PMID: 17250645
-
Toxicological assessment of Ashitaba Chalcone.Food Chem Toxicol. 2015 Mar;77:111-9. doi: 10.1016/j.fct.2014.12.021. Epub 2015 Jan 7. Food Chem Toxicol. 2015. PMID: 25576957 Review.
-
Possible antithrombotic effects of Angelica keiskei (Ashitaba).Pharmazie. 2018 Jun 1;73(6):315-317. doi: 10.1691/ph.2018.8370. Pharmazie. 2018. PMID: 29880082 Review.
Cited by
-
Protective effects of an ethanol extract of Angelica keiskei against acetaminophen-induced hepatotoxicity in HepG2 and HepaRG cells.Nutr Res Pract. 2017 Apr;11(2):97-104. doi: 10.4162/nrp.2017.11.2.97. Epub 2017 Mar 10. Nutr Res Pract. 2017. PMID: 28386382 Free PMC article.
-
Angelica keiskei Impacts the Lifespan and Healthspan of Drosophila melanogaster in a Sex and Strain-Dependent Manner.Pharmaceuticals (Basel). 2023 May 12;16(5):738. doi: 10.3390/ph16050738. Pharmaceuticals (Basel). 2023. PMID: 37242522 Free PMC article.
-
The pharmacology activities of Angelica keiskei Koidzumi and its efficacy and safety in humans.Heliyon. 2024 Jan 13;10(2):e24119. doi: 10.1016/j.heliyon.2024.e24119. eCollection 2024 Jan 30. Heliyon. 2024. PMID: 38357325 Free PMC article. Review.
-
Angelica keiskei, an emerging medicinal herb with various bioactive constituents and biological activities.Arch Pharm Res. 2017 Jun;40(6):655-675. doi: 10.1007/s12272-017-0892-3. Epub 2017 Apr 24. Arch Pharm Res. 2017. PMID: 28439780 Free PMC article. Review.
-
The role of chalcones in suppression of NF-κB-mediated inflammation and cancer.Int Immunopharmacol. 2011 Mar;11(3):295-309. doi: 10.1016/j.intimp.2010.12.006. Epub 2010 Dec 22. Int Immunopharmacol. 2011. PMID: 21184860 Free PMC article. Review.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
