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. 2008 Jul;71(7):1308-10.
doi: 10.1021/np800187f. Epub 2008 Jun 18.

C-geranylated chalcones from the stems of Angelica keiskei with superoxide-scavenging activity

Nobuwa Aoki  1 , Mai Muko, Emi Ohta, Shinji Ohta
Affiliations

C-geranylated chalcones from the stems of Angelica keiskei with superoxide-scavenging activity

Nobuwa Aoki et al. J Nat Prod. 2008 Jul.

Abstract

An ethyl acetate-soluble fraction of a methanol extract from the stems of Angelica keiskei was subjected to chromatographic separation to give three new chalcones, designated as xanthokeismins A-C (1-3), in addition to a known chalcone, xanthoangelol B (4). The structures of 1-3 were determined on the basis of the analysis of their spectroscopic data. Compounds 1-4 exhibited potent superoxide-scavenging activity.

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