Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2008 Mar;42(1):42-4.

Congenital nephrotic syndrome of the finnish type

Ev Badoe  1 , R Kumoji
Affiliations

Congenital nephrotic syndrome of the finnish type

Ev Badoe et al. Ghana Med J. 2008 Mar.

Abstract

SummaryCongenital Nephrotic Syndrome of the Finish type (CNF) is a rare and severe disease. A neonate with CNF is described. The diagnosis carries a dramatically poorer prognosis than nephrotic syndrome diagnosed after one year. The clinical course is one of persistent oedema and recurrent infections leading to death. The gene for the Finish type has been mapped to the long arm of chromosome 19. Case reports show it to be responsive to captopril and indomethacin. It is uniformly resistant to steroids and immunosuppressive drugs.

Keywords: Congenital nephrotic syndrome of the Finnish type (CNF); captopril; indomethacin.

PubMed Disclaimer

References

    1. Arneli GC. The nepthrotic syndrome. Pediatr Clin North Am. 1971;18:547–559. - PubMed
    1. Holmberg C, Laine J, Ronholm K, et al. Congenital Nephrotic Syndrome. Kidney Int. 1996;49(53):S51–S56. - PubMed
    1. Savage JM, Jefferson JA, Maxwell AP, Hughes AE, Shanks JH, Gill D. Improved prognosis for congenital nephrotic syndrome of the Finnish type in Irish families. Arch Dis Child. 1999;80:466–469. - PMC - PubMed
    1. Fuchuber A, Niaudet P, Gribouval O, et al. Congenital nephrotic syndrome of the Finnish type: linkage to the locus in non-Finnish Families. J Am Soc Nephrol. 1966;12:1–94.
    1. Norio R. Heredity in congenital nephrotic syndrome. Ann Paediatr Fenn. 1966;12:1–94. - PubMed

LinkOut - more resources