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Case Reports
. 2008 Jun 14;14(22):3591-3.
doi: 10.3748/wjg.14.3591.

Ischemic colitis associated with intestinal vasculitis: histological proof in systemic lupus erythematosus

Jeong-Rok Lee  1 , Chang-Nyol Paik, Jin-Dong Kim, Woo-Chul Chung, Kang-Moon Lee, Jin-Mo Yang
Affiliations
Case Reports

Ischemic colitis associated with intestinal vasculitis: histological proof in systemic lupus erythematosus

Jeong-Rok Lee et al. World J Gastroenterol. .

Abstract

Ischemic colitis is an uncommon complication in patients with systemic lupus erythematosus (SLE). In previously reported cases of colitis caused by SLE, intestinal vasculitis is implicated as the causative process, but is rarely confirmed histologically. We described a case of a 32-year-old man with increased activity of SLE, who presented with hematochezia and abdominal pain due to ischemic colitis with small vessel vasculitis which was proven by sigmoidoscopic biopsy. The clinical course of the patient was improved after steroid and conservative management.

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Figures

Figure 1
Figure 1
Sigmoidoscopy shows the severe erythematous friable mucosa and diffuse ulceration with dirty exudates.
Figure 2
Figure 2
Microscopy of colon biopsies shows the thickening of small vessel wall and lymphocyte infiltration around vessels (HE, × 400).
See this image and copyright information in PMC

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