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. 2008 Aug;71(8):1451-4.
doi: 10.1021/np800212g. Epub 2008 Jun 24.

Agelasines J, K, and L from the Solomon Islands Marine Sponge Agelas cf. mauritiana

Jérôme Appenzeller  1 , Ghezala Mihci, Marie-Thérèse Martin, Jean-François Gallard, Jean-Louis Menou, Nicole Boury-Esnault, John Hooper, Sylvain Petek, Severine Chevalley, Alexis Valentin, Anne Zaparucha, Ali Al-Mourabit, Cécile Debitus
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Agelasines J, K, and L from the Solomon Islands Marine Sponge Agelas cf. mauritiana

Jérôme Appenzeller et al. J Nat Prod. 2008 Aug.

Abstract

Three new diterpene alkaloids, agelasine J (3), agelasine K (4), and agelasine L (5), were isolated from the marine sponge Agelas cf. mauritiana collected in the Solomon Islands. The structures of these compounds were elucidated by physical data analyses. They displayed in vitro antimalarial activity against Plasmodium falciparum.

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