Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2008 Sep;43(1):123-5.
doi: 10.1016/j.jcv.2008.05.003. Epub 2008 Jun 24.

Age-related pattern of KI and WU polyomavirus infection

B Abedi Kiasari  1 , P J Vallely, C E Corless, M Al-Hammadi, P E Klapper
Affiliations

Age-related pattern of KI and WU polyomavirus infection

B Abedi Kiasari et al. J Clin Virol. 2008 Sep.

Abstract

Background: The role of two recently identified polyomaviruses, KI and WU, in the causation of respiratory disease has not been established.

Objectives: To determine the prevalence of KI and WU viruses (KIV and WUV) in 371 respiratory samples and evaluate their contribution to respiratory disease.

Study design: Specimens were screened for KIV and WUV using single, multiplex or real time PCR; co-infection with other respiratory viruses was evaluated.

Results: Of the 371 samples analysed, 10 (2.70%) were positive for KIV and 4 (1.08%) were positive for WUV yielding an overall case prevalence of KIV and WUV infection of 3.77%. KIV and WUV were identified in patients aged<15 years (11 patients) with upper or lower respiratory tract infection and >45 years (3 patients) with upper respiratory tract infection. Co-infections were found in 5 (50%) and 3 (75%) of the KIV and WUV positive samples, respectively.

Conclusions: This study supports previous conclusions that KIV and WUV detection in the respiratory tract may be coincidental and reflect reactivation of latent or persistent infection with these viruses. The age distribution of KIV and WUV infection in this study mirrors that found for the other human polyomaviruses, BK and JC.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Co-detection of KIV and WUV with other respiratory viruses.
See this image and copyright information in PMC

References

    1. Allander T., Andreasson K., Gupta S., Bjerkner A., Bogdanovic G., Persson M.A. Identification of a third human polyomavirus. J Virol. 2007;81:4130–4136. - PMC - PubMed
    1. Gaynor A.M., Nissen M.D., Whiley D.M., Mackay I.M., Lambert S.B., Wu G. Identification of a novel polyomavirus from patients with acute respiratory tract infections. PLoS Pathogens. 2007;3:e64. - PMC - PubMed
    1. Bialasiewicz S., Whiley D.M., Lambert S.B., Wang D., Nissen M.D., Sloots T.P. A newly reported human polyomavirus, KI virus, is present in the respiratory tract of Australian children. J Clin Virol. 2007;40:15–18. - PMC - PubMed
    1. Norja P., Ubillos I., Templeton K., Simmonds P. No evidence for an association between infections with WU and KI polyomaviruses and respiratory disease. J Clin Virol. 2007;40:307–311. - PMC - PubMed
    1. Han T.H., Chung J., Koo J.W., Kim S.W., Hwang E.S. WU polyomavirus in children with acute lower respiratory tract infections, South Korea. Emerg Infect Dis. 2007;13:1766–1768. - PMC - PubMed

MeSH terms