Cancer of the breast: 5-year survival in a tertiary hospital in Uganda
- PMID: 18577991
- PMCID: PMC2453032
- DOI: 10.1038/sj.bjc.6604435
Cancer of the breast: 5-year survival in a tertiary hospital in Uganda
Abstract
The objective was to investigate survival of breast cancer patients at Mulago Hospital. A retrospective study of the medical records of 297 breast cancer patients referred to the combined breast clinic housed in the radiotherapy department between 1996 and 2000 was done. The female/male ratio was 24 : 1. The age range was 22-85 years, with a median of 45 years and peak age group of 30-39 years. Twenty-three percent had early disease (stages 0-IIb) and 26% had metastatic disease. Poorly differentiated was the most common pathological grade (58%) followed by moderately differentiated (33%) and well-differentiated (9%) tumours. The commonest pathological type encountered was 'not otherwise specified' (76%). Of all patients, 75% had surgery, 76% had radiotherapy, 60% had hormonotherapy and 29% had chemotherapy. Thirty-six (12%) patients received all the four treatment modalities. The 5-year survival probabilities (Kaplan-Meier) for early disease were 74 and 39% for advanced disease (P=0.001). The overall 5-year survival was 56%, which is lower than the rates in the South African blacks (64%) and North American whites (82-88%).
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References
-
- Althuis MD, Dozier JM, Anderson WF, Devesa SS, Brinton LA (2005) Global trends in breast cancer incidence and mortality 1973–1997. Int J Epidemiol 34(2): 405–412 - PubMed
-
- American Cancer Society (ACS) (2006) Cancer facts and figures. www.acs.org
-
- American Joint Committee on Cancer (2002) Chapter on breast. In AJCC Cancer Staging Manual, Greene FL, Page DL, Fleming ID, Fritz AG, Balch CM, Haller DG, Morrow M (eds) AJCC 6th edn, pp 221–240. Lippincott-Raven: Philadelphia
-
- Amir H, Makwaya CK, Moshiro C, Kwesigabo G (1996) Carcinoma of the male breast: a sexually transmitted disease. East Afr Med J 73: 187–190 - PubMed
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