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Comparative Study
. 2008 Sep 1;24(17):1963-5.
doi: 10.1093/bioinformatics/btn319. Epub 2008 Jun 25.

Comparing simulation results of SBML capable simulators

Affiliations
Comparative Study

Comparing simulation results of SBML capable simulators

Frank T Bergmann et al. Bioinformatics. .

Abstract

Motivation: Simulations are an essential tool when analyzing biochemical networks. Researchers and developers seeking to refine simulation tools or develop new ones would benefit greatly from being able to compare their simulation results.

Summary: We present an approach to compare simulation results between several SBML capable simulators and provide a website for the community to share simulation results.

Availability: The website with simulation results and additional material can be found under: http://sys-bio.org/sbwWiki/compare. The software used to generate the simulation results is available on the website for download.

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Figures

Fig. 1.
Fig. 1.
Simulation Results for BioModel #24 (Left) The viewer application, displaying the simulation results (lower panel) and differences between them (upper panel) (Right) An online viewer application is available to view all results customized to a researcher's interest, see http://sys-bio.org/sbwWiki/compare/.
Fig. 2.
Fig. 2.
Percent agreement between simulation results: only 10% of the simulation results have an agreement factor smaller than <70%. (100% agreement: 63%, 90–99% agreement: 15%, 80–90% agreement: 12{%).

References

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    1. Evans T, et al. The SBML discrete stochastic models test suite. Bioinformatics. 2007;24:285–286. - PubMed

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