Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Multicenter Study
. 2009 Mar;20(3):385-92.
doi: 10.1007/s00198-008-0671-6. Epub 2008 Jun 26.

Osteoporotic fractures and hospitalization risk in chronic spinal cord injury

Affiliations
Multicenter Study

Osteoporotic fractures and hospitalization risk in chronic spinal cord injury

L R Morse et al. Osteoporos Int. 2009 Mar.

Abstract

Osteoporosis is a well acknowledged complication of spinal cord injury. We report that motor complete spinal cord injury and post-injury alcohol consumption are risk factors for hospitalization for fracture treatment. The clinical assessment did not include osteoporosis diagnosis and treatment considerations, indicating a need for improved clinical protocols.

Introduction: Treatment of osteoporotic long bone fractures often results in lengthy hospitalizations for individuals with spinal cord injury. Clinical features and factors that contribute to hospitalization risk have not previously been described.

Methods: Three hundred and fifteen veterans > or = 1 year after spinal cord injury completed a health questionnaire and underwent clinical exam at study entry. Multivariate Cox regression accounting for repeated events was used to assess longitudinal predictors of fracture-related hospitalizations in Veterans Affairs Medical Centers 1996-2003.

Results: One thousand four hundred and eighty-seven hospital admissions occurred among 315 participants, and 39 hospitalizations (2.6%) were for fracture treatment. Median length of stay was 35 days. Fracture-related complications occurred in 53%. Independent risk factors for admission were motor complete versus motor incomplete spinal cord injury (hazard ratio = 3.73, 95% CI = 1.46-10.50). There was a significant linear trend in risk with greater alcohol consumption after injury. Record review indicated that evaluation for osteoporosis was not obtained during these admissions.

Conclusions: Assessed prospectively, hospitalization in Veterans Affairs Medical Centers for low-impact fractures is more common in motor complete spinal cord injury and is associated with greater alcohol use after injury. Osteoporosis diagnosis and treatment considerations were not part of a clinical assessment, indicating the need for improved protocols that might prevent low-impact fractures and related admissions.

PubMed Disclaimer

Conflict of interest statement

Conflicts of interest None.

Similar articles

Cited by

References

    1. Kanis JA. Diagnosis of osteoporosis and assessment of fracture risk. Lancet. 2002 June 1;359(9321):1929–1936. - PubMed
    1. Dauty M, Perrouin VB, Maugars Y, Dubois C, Mathe JF. Supralesional anmesional bone mineral density in spinal cordinjured patients. Bone. 2000 August;27(2):305–309. - PubMed
    1. Frey-Rindova P, de Bruin ED, Stussi E, Dambacher MA, Dietz V. Bone mineral density in upper and lower extremities during 12 months after spinal cord injury measured by peripheral quantitative computed tomography. Spinal Cord. 2000 January;38(1):26–32. - PubMed
    1. Garland DE, Stewart CA, Adkins RH, Hu SS, Rosen C, Liotta FJ, Weinstein DA. Osteoporosis after spinal cord injury. J Orthop Res. 1992 May;10(3):371–378. - PubMed
    1. Barrett-Connor E. The economic and human costs of osteoporotic fracture. Am J Med. 1995 February 27;98(2A):3S–8S. - PubMed

Publication types