Low dose of lidocaine: comparison of 15 with 20 mg/ml with dextrose for spinal anesthesia in lithotomy position and ambulatory surgery
- PMID: 18582308
- DOI: 10.1111/j.1399-6576.2007.01511.x
Low dose of lidocaine: comparison of 15 with 20 mg/ml with dextrose for spinal anesthesia in lithotomy position and ambulatory surgery
Abstract
Background: Spinal anesthesia with the local anesthetic lidocaine has come under scrutiny because it is associated with transient neurologic symptoms (TNS). Although TNS is not associated with either lidocaine concentration or dose, its incidence has never been examined with very small doses of hyperbaric spinal lidocaine in patients in the lithotomy position. We designed this study prospectively to compare the efficacy of low-dose 15 mg/ml with low-dose 20 mg/ml hyperbaric lidocaine in patients undergoing elective outpatient surgery in the lithotomy position.
Methods: A total of 100 patients were randomized to receive either 30 mg of 15 mg/ml or the same dose of 20 mg/ml hyperbaric lidocaine. Lidocaine density at 37 degrees C is 1.0241 g/ml for the 15 mg/ml and 1.0260 g/ml for the 20 mg/ml solution. Patients were examined for motor block, sensory block, and block duration. Patients were contacted at 24, 48 and 72 h and questioned about their perceptions of pain after the spinal anesthesia with specific questions designed to diagnose TNS.
Results: The spread of analgesia was the same with both solutions of lidocaine. Motor block was incomplete in all patients in both groups. TNS were not observed when low doses of both solutions of lidocaine with dextrose were used in these ambulatory patients in the lithotomy position.
Conclusion: Hyperbaric lidocaine results in rapid recovery from sensory block and motor blockade. It may have advantages for patients in a day-case setting. No patients complained of TNS after discharge.
Similar articles
-
Anesthetic and recovery profiles of lidocaine versus mepivacaine for spinal anesthesia in patients undergoing outpatient orthopedic arthroscopic procedures.J Clin Anesth. 2012 Mar;24(2):109-15. doi: 10.1016/j.jclinane.2011.06.014. Epub 2012 Feb 17. J Clin Anesth. 2012. PMID: 22342508 Clinical Trial.
-
Low-dose 3 mg levobupivacaine plus 10 microg fentanyl selective spinal anesthesia for gynecological outpatient laparoscopy.Anesth Analg. 2009 Nov;109(5):1456-61. doi: 10.1213/ANE.0b013e3181ba792e. Anesth Analg. 2009. PMID: 19843783 Clinical Trial.
-
Dose response relationships for isobaric spinal mepivacaine using the combined spinal epidural technique.Anesth Analg. 1999 Nov;89(5):1167-71. Anesth Analg. 1999. PMID: 10553828 Clinical Trial.
-
Optimizing spinal anesthesia for ambulatory surgery.Reg Anesth. 1997 Nov-Dec;22(6):500-10. Reg Anesth. 1997. PMID: 9425964 Review.
-
Revival of old local anesthetics for spinal anesthesia in ambulatory surgery.Curr Opin Anaesthesiol. 2011 Dec;24(6):633-7. doi: 10.1097/ACO.0b013e32834aca1b. Curr Opin Anaesthesiol. 2011. PMID: 21841475 Review.
Cited by
-
Transient neurological symptoms (TNS) following spinal anaesthesia with lidocaine versus other local anaesthetics in adult surgical patients: a network meta-analysis.Cochrane Database Syst Rev. 2019 Dec 1;12(12):CD003006. doi: 10.1002/14651858.CD003006.pub4. Cochrane Database Syst Rev. 2019. PMID: 31786810 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources