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. 1976 Aug 30;86(3):307-13.
doi: 10.1007/BF00286950.

[Differing carcinogenic activity in BD-rats of 1-phenyl- and 1-(pyridyl-3)-3,3-diethyltriazene after single doses on 1., 10. or 30. day of life (author's transl)]

[Article in German]
S Ivankovic, R Port, R Preussmann

[Differing carcinogenic activity in BD-rats of 1-phenyl- and 1-(pyridyl-3)-3,3-diethyltriazene after single doses on 1., 10. or 30. day of life (author's transl)]

[Article in German]
S Ivankovic et al. Z Krebsforsch Klin Onkol Cancer Res Clin Oncol. .

Abstract

1-Phenyl- and 1-(pyridyl-3)-3,3-diethyltriazene have been investigated for carcinogenic effects in BD-rats after subcutaneous injection of a single dose of 50 mg of the compounds on day 1, 10, or 30 of life. The phenyl derivative showed a lower carcinogenic activity in comparison with the pyridyltriazene. Predominantly neurogenic tumors were observed. These were seen much more on treatment on day 1 or 10 of life than on treatment on day 30. The results confirm that the nervous system of rats is a target organ predominantly during early postnatal life.

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References

    1. Z Krebsforsch. 1970;74(2):141-61 - PubMed
    1. Proc Soc Exp Biol Med. 1955 Nov;90(2):484-9 - PubMed
    1. Proc Soc Exp Biol Med. 1955 Nov;90(2):489-94 - PubMed
    1. Naturwissenschaften. 1967 Apr;54(7):171 - PubMed
    1. Mutat Res. 1971 Apr;11(4):397-410 - PubMed

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