YKL-40: a candidate biomarker for simian immunodeficiency virus and human immunodeficiency virus encephalitis?
- PMID: 18583323
- PMCID: PMC2438282
- DOI: 10.2353/ajpath.2008.080389
YKL-40: a candidate biomarker for simian immunodeficiency virus and human immunodeficiency virus encephalitis?
Abstract
This Commentary explores the possible role for YKL-40, a secreted mammalian chitinase-like protein, as a predictive biomarker for SIV encephalitis (SIVE) and HIV encephalitis (HIVE).
Comment on
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YKL-40, a marker of simian immunodeficiency virus encephalitis, modulates the biological activity of basic fibroblast growth factor.Am J Pathol. 2008 Jul;173(1):130-43. doi: 10.2353/ajpath.2008.080045. Epub 2008 Jun 13. Am J Pathol. 2008. PMID: 18556781 Free PMC article.
References
-
- UNAIDS/WHO report highlights epidemic resurgence, AIDS Alert 2007, 22 (Suppl):1–3 - PubMed
-
- Sacktor N, McDermott MP, Marder K, Schifitto G, Selnes OA, McArthur JC, Stern Y, Albert S, Palumbo D, Kieburtz K, De Marcaida JA, Cohen B, Epstein L. HIV-associated cognitive impairment before and after the advent of combination therapy. J Neurovirol. 2002;8:136–142. - PubMed
-
- Antinori A, Arendt G, Becker JT, Brew BJ, Byrd DA, Cherner M, Clifford DB, Cinque P, Epstein LG, Goodkin K, Gisslen M, Grant I, Heaton RK, Joseph J, Marder K, Marra CM, McArthur JC, Nunn M, Price RW, Pulliam L, Robertson KR, Sacktor N, Valcour V, Wojna VE. Updated research nosology for HIV-associated neurocognitive disorders. Neurology. 2007;69:1789–1799. - PMC - PubMed
-
- Brew BJ, Gonzalez-Scarano F. HIV-associated dementia: an inconvenient truth. Neurology. 2007;68:324–325. - PubMed
-
- Bonneh-Barkay D, Bissel SJ, Wang G, Fish KN, Nicholl GCB, Darko SW, Medina-Flores R, Murphey-Corb M, Rajakumar PA, Nyaundi J, Mellors JW, Bowser R, Wiley CA. YKL-40, a marker of SIV encephalitis, modulates the biological activity of basic fibroblast growth factor. Am J Pathol. 2008;173:xxx–xxx. - PMC - PubMed
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