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. 2008 Sep;23(9):2056-63.
doi: 10.1093/humrep/den154. Epub 2008 Jun 25.

Prevalence of psychiatric disorders in infertile women and men undergoing in vitro fertilization treatment

H Volgsten  1 , A Skoog Svanberg, L Ekselius, O Lundkvist, I Sundström Poromaa
Affiliations

Prevalence of psychiatric disorders in infertile women and men undergoing in vitro fertilization treatment

H Volgsten et al. Hum Reprod. 2008 Sep.

Abstract

Background: This study was undertaken to determine the prevalence of psychiatric disorders in infertile women and men undergoing in vitro fertilization (IVF) treatment.

Methods: Participants were 1090 consecutive women and men, 545 couples, attending a fertility clinic in Sweden during a two-year period. The Primary Care Evaluation of Mental Disorders (PRIME-MD), based on the Diagnostic and Statistical Manual of Mental Disorders, 4th edn (DSM-IV), was used as the diagnostic tool for evaluating mood and anxiety disorders.

Results: Overall, 862 (79.1%) subjects filled in the PRIME-MD patient questionnaire. Any psychiatric diagnosis was present in 30.8% of females and in 10.2% of males in the study sample. Any mood disorder was present in 26.2% of females and 9.2% of males. Major depression was the most common mood disorder, prevalent in 10.9% of females and 5.1% of males. Any anxiety disorder was encountered in 14.8% of females and 4.9% males. Only 21% of the subjects with a psychiatric disorder according to DSM-IV received some form of treatment.

Conclusions: Mood disorders are common in both women and men undergoing IVF treatment. The majority of subjects with a psychiatric disorder were undiagnosed and untreated.

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Figures

Figure 1:
Figure 1:
The study population consisted of screen negative, screen positive and diagnosed subjects, n = 825 (413 females and 412 males).
See this image and copyright information in PMC

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