Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2008 Jun 30:2:222.
doi: 10.1186/1752-1947-2-222.

Long-term survival in a patient with repeated resections for lung metastasis after hepatectomy for ruptured hepatocellular carcinoma: a case report

Kai-Lun Shih  1 , Yang-Yuan Chen, Tsung-Han Teng, Maw-Soan Soon
Affiliations

Long-term survival in a patient with repeated resections for lung metastasis after hepatectomy for ruptured hepatocellular carcinoma: a case report

Kai-Lun Shih et al. J Med Case Rep. .

Abstract

Introduction: Tumor rupture and pulmonary metastasis in patients with hepatocellular carcinoma are both associated with poor prognosis and treatment strategies are controversial.

Case presentation: Here we report a 50-year-old man with survival of over 90 months after undergoing an extended right lobectomy for a ruptured hepatocellular carcinoma and then repeated resections for pulmonary metastasis during the followup period.

Conclusion: This case report shows that surgical resection can be an effective treatment for patients with both ruptured hepatocellular carcinoma and pulmonary recurrences.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Abdominal computed tomography on admission showing a mass in Couinaud segment 7 and segment 8 of the liver and intraperitoneal fluid.
Figure 2
Figure 2
2a: Polygonal cells with higher N/C (nucleus-to-cytoplasm) ratio than normal, abundant granular eosinophilic cytoplasm, round nuclei with coarse chromatin and an area of giant cell (original magnification ×100). -2b: Metastatic hepatocellular carcinoma in lung parenchyma (original magnification ×40).
Figure 3
Figure 3
Chest computed tomography showing lung metastasis with pleural seeding 80 months after hepatectomy.
See this image and copyright information in PMC

References

    1. Zhu LX, Wang GS, Fan ST. Spontaneous rupture of hepatocellular carcinoma. Br J Surg. 1996;83:602–607. doi: 10.1002/bjs.1800830507. - DOI - PubMed
    1. Yamagata M, Maeda T, Ikeda Y, Shirabe K, Nishizaki T, Koyanagi N. Surgical results of spontaneously ruptured hepatocellular carcinoma. Hepatogastroenterology. 1995;42:461–464. - PubMed
    1. Chen CY, Lin XZ, Shin JS, Lin CY, Leow TC, Chen CY, Chang TT. Spontaneous rupture of hepatocellular carcinoma. A review of 141 Taiwanese cases and comparison with nonrupture cases. J Clin Gastroenterol. 1995;21:238–242. doi: 10.1097/00004836-199510000-00015. - DOI - PubMed
    1. Chen WK, Chang YT, Chung YT, Yang HR. Outcomes of emergency treatment in ruptured hepatocellular carcinoma in the ED. Am J Emerg Med. 2005;23:730–736. doi: 10.1016/j.ajem.2005.02.052. - DOI - PubMed
    1. Chiappa A, Zbar A, Audisio RA, Paties C, Bertani E, Staudacher C. Emergency liver resection for ruptured hepatocellular carcinoma complicating cirrhosis. Hepatogastroenterology. 1999;46:1145–1150. - PubMed

LinkOut - more resources