The International Subarachnoid Aneurysm Trial II: comparison of clipping vs coiling: key questions. Are the results of the study generalizable? Should clipping be done for patients less than 40 years of age?

Editorial

James I Ausman. Surg Neurol. 2008 Jul.

. 2008 Jul;70(1):104-7.

doi: 10.1016/j.surneu.2008.04.019.

No abstract available

Comment on

International subarachnoid aneurysm trial (ISAT) of neurosurgical clipping versus endovascular coiling in 2143 patients with ruptured intracranial aneurysms: a randomised comparison of effects on survival, dependency, seizures, rebleeding, subgroups, and aneurysm occlusion.
Molyneux AJ, Kerr RS, Yu LM, Clarke M, Sneade M, Yarnold JA, Sandercock P; International Subarachnoid Aneurysm Trial (ISAT) Collaborative Group. Molyneux AJ, et al. Lancet. 2005 Sep 3-9;366(9488):809-17. doi: 10.1016/S0140-6736(05)67214-5. Lancet. 2005. PMID: 16139655 Clinical Trial.
Could late rebleeding overturn the superiority of cranial aneurysm coil embolization over clip ligation seen in the International Subarachnoid Aneurysm Trial?
Mitchell P, Kerr R, Mendelow AD, Molyneux A. Mitchell P, et al. J Neurosurg. 2008 Mar;108(3):437-42. doi: 10.3171/JNS/2008/108/3/0437. J Neurosurg. 2008. PMID: 18312088 Clinical Trial.