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. 1995 Oct;1(2):97-102.
doi: 10.1016/1353-8020(95)00002-x.

Intermediate scale for assessment of Parkinson's disease. Characteristics and structure

Cooperative Multicentric Group  1 ; P Martínez-Martin, A Gil-Nagel, L Morlán Gracia, J Balseiro Gómez, F J Martínez-Sarriés, F Bermejo, T Del Ser Quijano, M C Macías, C Jiménez-Rojas, E Marañón, J M Grau Veciana, C Roig Arnall, O Bruna, C Junquéplaja, S Giménez-Roldán, J A Burguera
Affiliations

Intermediate scale for assessment of Parkinson's disease. Characteristics and structure

Cooperative Multicentric Group et al. Parkinsonism Relat Disord. 1995 Oct.

Abstract

The present study is devoted to the verification of the basic metrical characteristics of the ISAPD. One hundred and sixty-seven Parkinson's disease (PD) patients were included. Group A (n = 40) was simultaneously assessed by five raters who applied the ISAPD and other PD rating scales (PDRS). A set of timed tests, the MiniMental State Examination (MMSE) and the Hamilton Scale for Depression (HSD) were administered by an independent examiner. Group B (n = 127) was individually assessed through the UPDRS and the other PDRSs by separate neurologists in four different hospitals. The ISAPD was administered in 7.0 +/- 3.7 min. The internal consistency of this scale was high (Cronbach's alpha = 0.97). The inter-rater reliability of their items was very satisfactory (for all items, kappa > 0.70). There was a high correlation with the Hoehn and Yahr classification (r(s) = 0.71; p < 0.001) and some timed tests. The convergent validity with the other PDRS (UPDRS and Schwab and England Scale) was also very high (r(s) = 0.83-0.92; p < 0.001). The ISAPD also correlated with the MMSE and the HSD. Factor analysis identified three factors (activities of daily living; gait and mobility; speech and eating) that explained 76% of the variance. The ISAPD is an easy to apply, reliable, and valid scale that fulfills the aim for which it was designed.

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