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. 2008 Jul-Aug;8(4):85-9.
doi: 10.1111/j.1535-7511.2008.00249.x.

Imaging the brain's highways-diffusion tensor imaging in epilepsy

John S Duncan  1
Affiliations

Imaging the brain's highways-diffusion tensor imaging in epilepsy

John S Duncan. Epilepsy Curr. 2008 Jul-Aug.

Abstract

Diffusion tensor imaging evaluates the motion of water at the voxel level and can provide data on the structural integrity of brain tissue, with quantitative measures of diffusion and fractional anisotropy. Imaging of the orientation of preferential diffusion of water in the brain can visualize major white matter pathways and infer the structural basis of cerebral networks. Thus, how these pathways and networks may be altered in specific epilepsy syndromes and in consequence to therapies can be assessed with the aid of these images.

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References

    1. Taylor DG, Bushell MC. The spatial mapping of translational diffusion coefficients by the NMR imaging technique. Phys Med Biol. 1985;30:345–349. - PubMed
    1. Basser PJ. Inferring microstructural features and the physiological state of tissues from diffusion-weighted images. NMR Biomed. 1995;8:333–344. - PubMed
    1. Le Bihan D, Mangin JF, Poupon C, Clark CA, Pappata S, Molko N, Chabriat H. Diffusion tensor imaging: concepts and applications. J.Magn Reson Imaging. 2001;13:534–546. - PubMed
    1. Beaulieu C. The basis of anisotropic water diffusion in the nervous system—a technical review. NMR Biomed. 2002;15:435–455. - PubMed
    1. Zhong J, Petroff OA, Pleban LA, Gore JC, Prichard JW. Reversible, reproducible reduction of brain water apparent diffusion coefficient by cortical electroshocks. Magn Reson Med. 1997;37:1–6. - PubMed