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Review
. 2008 Dec 8;364(2):176-87.
doi: 10.1016/j.ijpharm.2008.05.014. Epub 2008 May 21.

Are pharmaceutics really going supercritical?

Irene Pasquali  1 , Ruggero Bettini
Affiliations
Review

Are pharmaceutics really going supercritical?

Irene Pasquali et al. Int J Pharm. .

Abstract

The present work focuses on some applications of supercritical fluids in the pharmaceutical field, provides a critical review of the most recent advances and aims to give a vision on the future of this technology. In particular, processes such as particle and crystal engineering, formation of cyclodextrin complexes, coating, foaming and tissue engineering, extrusion, production of liposomes, formulation of biotechnological compounds, sterilization and solvent removal are described and discussed.

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