Comment
doi: 10.1016/j.ccr.2008.06.012.
Deregulating EMT and senescence: double impact by a single twist
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- PMID: 18598938
- DOI: 10.1016/j.ccr.2008.06.012
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Comment
Deregulating EMT and senescence: double impact by a single twist
Cancer Cell.
.
Free article
Abstract
The acquisition of a fully malignant phenotype is limited by several barriers, including cellular senescence and the requirement to undergo an epithelial-mesenchymal transition (EMT). Deregulation of these processes is believed to occur by largely independent events. In this issue of Cancer Cell, Ansieau et al. (2008) challenge this view.
Comment on
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Induction of EMT by twist proteins as a collateral effect of tumor-promoting inactivation of premature senescence.Cancer Cell. 2008 Jul 8;14(1):79-89. doi: 10.1016/j.ccr.2008.06.005. Cancer Cell. 2008. PMID: 18598946
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